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Smoking Affect the Cilia

January 19th 2012 06:55
Cilia are tiny hair-like organelles that reside on the surface of cells for the purpose of sweeping debris away from lung and nasal cavities. Cilia also line the Eustachian tubes, and sinuses, as well as the fallopian tubes in women. For each ciliated cell in the body, there are between 100 and 200 cilia, each one anchored by another organelle known as the basal body. Constructed of hollow cylindrical microtubules, each basal body is arranged in the same orientation to allow the movement of fluid and particles to occur in one direction.

The most common reason to suffer damaged or paralyzed cilia, however, is smoking. The cumulative effect of smoking on the cilia is that dirt, environmental pollutants, and toxins from cigarette smoke remain in the lungs.


Continued smoking may eventually lead to chronic obstructive pulmonary disease (COPD, including chronic bronchitis and emphysema) or lung cancer. In fact, smoking eventually destroys the cilia, which may then be displaced by an excessive number of basal cells, or cancerous squamous cells. Over time, these cells may become cancerous. They may also become rogue, escaping through lung tissue and invading other parts of the body.

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